LEAD/DRUG DISCOVERY FROM NATURAL RESOURCES

Lead/Drug Discovery from Natural Resources

Natural products and their derivatives have been shown to be effective drug candidates against various diseases for Whips many years.Over a long period of time, nature has produced an abundant and prosperous source pool for novel therapeutic agents with distinctive structures.Major natural-product-based drugs approved for clinical use include anti-

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IMPACTS OF THE PUBLIC PROCUREMENT ACT 2007 ON THE PROCUREMENT OF PUBLIC PROJECTS IN NIGERIAN TERTIARY INSTITUTIONS

Tertiary institutions often require huge investments in capital projects for effective learning to be actualized.In Nigeria, public tertiary institutions are usually funded fully by the Federal Government through interventionist institutions like Tetfund which are usually saddled with the responsibility of providing the fund required to achieve bot

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Case study of fire and explosion accident based on damage consequence and numerical results: Explosion medium traceability

Alcohol-based fuel is widely used in the catering industry due to the excellent economy, but its explosion risk has not been paid much attention in thermal engineering.In this paper, a serious fire accident caused by Chocolate Molds the leakage of civil alcohol-based fuel vapor in Northeast China is introduced in detail.A case study is carried out

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Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease

Excitotoxicity plays a key role in the selective vulnerability of striatal neurons in Huntington disease (HD).Decreased glutamate uptake by glial cells could account for the excess glutamate at the synapse in patients as well as animal models of HD.The major molecule responsible for clearing glutamate at the synapses is glial glutamate transporter

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